Exam\u00adples include\u00adco\u00adop\u00ader\u00ada\u00adtive acid-base catal\u00ady\u00adsis in which a Lewis acid and a basic func\u00adtion are anchore\u00addon a sil\u00adi\u00adca sur\u00adface, includ\u00ading SBA-15 and coor\u00addi\u00adnat\u00aded met\u00adal ions on the periph\u00adery of aden\u00addrimer. We have inves\u00adti\u00adgat\u00aded using nanocage struc\u00adtures to exam\u00adine the effect ofen\u00advi\u00adron\u00adment and dis\u00adcov\u00adered evi\u00addence of the \u201cpKa shift\u201d effect of amines groups insid\u00ade\u00adthe cage, pri\u00admar\u00adi\u00adly due to elec\u00adtro\u00adsta\u00adt\u00adic repul\u00adsion. These and oth\u00ader exam\u00adples will bedis\u00adcussed. 2008 Spring Sym\u00adpo\u00adsium Harold H. Kung Chem\u00adi\u00adcal and Bio\u00adlog\u00adi\u00adcal Engi\u00adneer\u00ading Depart\u00adment North\u00adwest\u00adern Uni\u00adver\u00adsi\u00adty, Evanston IL 60208\u20133120, USA Abstract \u2014 In nature, enzymes func\u00adtion effec\u00adtive\u00adly under mild con\u00addi\u00adtions of near neu\u00adtral pHand room tem\u00adper\u00ada\u00adture using com\u00admon organ\u00adic func\u00adtion\u00adal groups such as amines,hydroxyls, and car\u00adboxylic acids, which, when used out\u00adside the enzyme environment,exhibit activ\u00adi\u00adties many orders [\u2026]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[15],"tags":[52],"class_list":["post-652","post","type-post","status-publish","format-standard","hentry","category-abstracts","tag-symposium"],"_links":{"self":[{"href":"https:\/\/catalysisclubphilly.org\/awe9a91v\/wp-json\/wp\/v2\/posts\/652","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/catalysisclubphilly.org\/awe9a91v\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/catalysisclubphilly.org\/awe9a91v\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/catalysisclubphilly.org\/awe9a91v\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/catalysisclubphilly.org\/awe9a91v\/wp-json\/wp\/v2\/comments?post=652"}],"version-history":[{"count":9,"href":"https:\/\/catalysisclubphilly.org\/awe9a91v\/wp-json\/wp\/v2\/posts\/652\/revisions"}],"predecessor-version":[{"id":2481,"href":"https:\/\/catalysisclubphilly.org\/awe9a91v\/wp-json\/wp\/v2\/posts\/652\/revisions\/2481"}],"wp:attachment":[{"href":"https:\/\/catalysisclubphilly.org\/awe9a91v\/wp-json\/wp\/v2\/media?parent=652"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/catalysisclubphilly.org\/awe9a91v\/wp-json\/wp\/v2\/categories?post=652"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/catalysisclubphilly.org\/awe9a91v\/wp-json\/wp\/v2\/tags?post=652"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nHarold H. Kung<\/strong>
\nChem\u00adi\u00adcal and Bio\u00adlog\u00adi\u00adcal Engi\u00adneer\u00ading Depart\u00adment
\nNorth\u00adwest\u00adern Uni\u00adver\u00adsi\u00adty, Evanston
\nIL 60208\u20133120, USA<\/em>
\n
\nAbstract<\/strong> \u2014 In nature, enzymes func\u00adtion effec\u00adtive\u00adly under mild con\u00addi\u00adtions of near neu\u00adtral pHand room tem\u00adper\u00ada\u00adture using com\u00admon organ\u00adic func\u00adtion\u00adal groups such as amines,hydroxyls, and car\u00adboxylic acids, which, when used out\u00adside the enzyme environment,exhibit activ\u00adi\u00adties many orders of mag\u00adni\u00adtude low\u00ader. It is under\u00adstood that the enzymepro\u00adtein pro\u00advides an envi\u00adron\u00adment that is con\u00adducive to coop\u00ader\u00ada\u00adtive effect among the group\u00adsand hydropho\u00adbic\u00adi\u00adty at the active cen\u00adter. In con\u00adtrast, catal\u00ady\u00adsis in abi\u00adot\u00adic sys\u00adtems sel\u00addo\u00admu\u00adti\u00adlized such func\u00adtions, espe\u00adcial\u00adly het\u00adero\u00adge\u00adneous catal\u00ady\u00adsis. Instead, they rely on harshre\u00adac\u00adtion con\u00addi\u00adtions of ele\u00advat\u00aded tem\u00adper\u00ada\u00adtures and pres\u00adsures, and\/or strong acids and bases,with the con\u00adse\u00adquence of sac\u00adri\u00adfic\u00ading selec\u00adtiv\u00adi\u00adty. Recent\u00adly, advances in cat\u00ada\u00adlyst syn\u00adthe\u00adsistech\u00adniques make it increas\u00ading\u00adly pos\u00adsi\u00adble to design and syn\u00adthe\u00adsize abi\u00adot\u00adic sys\u00adtems that\u00adpos\u00adsess mul\u00adti\u00adple func\u00adtion\u00adal\u00adi\u00adties to achieve coop\u00ader\u00ada\u00adtive catal\u00ady\u00adsis.<\/p>\n
\n
\nSpeaker\u2019s Biog\u00adra\u00adphy<\/strong> \u2014 Dr. Kung is Pro\u00adfes\u00adsor at the Depart\u00adment of Chem\u00adi\u00adcal and Bio\u00adlog\u00adi\u00adcalEngi\u00adneer\u00ading, and Direc\u00adtor of the Cen\u00adter for Ener\u00adgy Effi\u00adcient Trans\u00adporta\u00adtion atNorth\u00adwest\u00adern Uni\u00adver\u00adsi\u00adty. His research goal is to search for and devel\u00adop the under\u00adly\u00ading\u00adchem\u00adi\u00adcal and engi\u00adneer\u00ading prin\u00adci\u00adples gov\u00adern\u00ading catal\u00ady\u00adsis, espe\u00adcial\u00adly regard\u00ading activ\u00adi\u00adty and\u00adprod\u00aduct selec\u00adtiv\u00adi\u00adty, and to make use of such knowl\u00adedge to design nov\u00adel and effi\u00adcient\u00adcat\u00ada\u00adlysts and process\u00ades.<\/p>\n","protected":false},"excerpt":{"rendered":"